Mercedes-Benz S 450 Gas Mileage (2018 - 2023): Comprehensive Fuel Economy Data

The Mercedes-Benz S 450 gas mileage is 20.5 to 26.5 miles per gallon as specified in our data below, organized by trim, option package, and model year.

For example, the 2023 Mercedes-Benz S 450 4MATIC trim model has a combined gas mileage of 20.5 miles per gallon, while the 2021 Mercedes-Benz S 450 has a combined gas mileage of 26.5 miles per gallon.

In the city, the S 450 gas mileage is 18 to 23 miles per gallon depending on the trim and model year.

On the highway, the S 450 gas mileage is 23 to 30 miles per gallon depending on the trim and model year.

Note: The gas mileage shown for hybrid vehicles is the miles per gallon equivalent.

Check out the Gas Mileage specifications for other makes and models.

2023 Mercedes-Benz S 450 Gas Mileage

Depending on trim level, the 2023 Mercedes-Benz S 450 gas mileage is from 20.5 to 26 miles per gallon combined.

In the city, the 2023 S 450 gas mileage is from 18 to 22 miles per gallon, depending on the trim.

On the highway, the 2023 S 450 gas mileage is from 23 to 30 miles per gallon, depending on the trim.

2022 Mercedes-Benz S 450 Gas Mileage

Depending on trim level, the 2022 Mercedes-Benz S 450 gas mileage is from 21 to 26 miles per gallon combined.

In the city, the 2022 S 450 gas mileage is from 18 to 22 miles per gallon, depending on the trim.

On the highway, the 2022 S 450 gas mileage is from 24 to 30 miles per gallon, depending on the trim.

2021 Mercedes-Benz S 450 Gas Mileage

Depending on trim level, the 2021 Mercedes-Benz S 450 gas mileage is from 22 to 26.5 miles per gallon combined.

In the city, the 2021 S 450 gas mileage is from 20 to 23 miles per gallon, depending on the trim.

On the highway, the 2021 S 450 gas mileage is from 24 to 30 miles per gallon, depending on the trim.

2020 Mercedes-Benz S 450 Gas Mileage

Depending on trim level, the 2020 Mercedes-Benz S 450 gas mileage is from 23 to 23.5 miles per gallon combined.

In the city, the 2020 S 450 gas mileage is from 18 to 19 miles per gallon, depending on the trim.

On the highway, the 2020 S 450 gas mileage is 28 miles per gallon.

2019 Mercedes-Benz S 450 Gas Mileage

Depending on trim level, the 2019 Mercedes-Benz S 450 gas mileage is from 23 to 23.5 miles per gallon combined.

In the city, the 2019 S 450 gas mileage is from 18 to 19 miles per gallon, depending on the trim.

On the highway, the 2019 S 450 gas mileage is 28 miles per gallon.

2018 Mercedes-Benz S 450 Gas Mileage

Depending on trim level, the 2018 Mercedes-Benz S 450 gas mileage is from 23 to 23.5 miles per gallon combined.

In the city, the 2018 S 450 gas mileage is from 18 to 19 miles per gallon, depending on the trim.

On the highway, the 2018 S 450 gas mileage is 28 miles per gallon.