The Mercedes-Benz S 450 gas mileage is 20.5 to 26.5 miles per gallon as specified in our data below, organized by trim, option package, and model year.
For example, the 2023 Mercedes-Benz S 450 4MATIC trim model has a combined gas mileage of 20.5 miles per gallon, while the 2021 Mercedes-Benz S 450 has a combined gas mileage of 26.5 miles per gallon.
In the city, the S 450 gas mileage is 18 to 23 miles per gallon depending on the trim and model year.
On the highway, the S 450 gas mileage is 23 to 30 miles per gallon depending on the trim and model year.
Note: The gas mileage shown for hybrid vehicles is the miles per gallon equivalent.
Check out the Gas Mileage specifications for other makes and models.
2023 Mercedes-Benz S 450 Gas Mileage
Depending on trim level, the 2023 Mercedes-Benz S 450 gas mileage is from 20.5 to 26 miles per gallon combined.
In the city, the 2023 S 450 gas mileage is from 18 to 22 miles per gallon, depending on the trim.
On the highway, the 2023 S 450 gas mileage is from 23 to 30 miles per gallon, depending on the trim.
2023 Mercedes-Benz S 450 Gas Mileage (Imperial)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| 4MATIC SUV |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
18 city mpg | 23 hwy mpg | 20.5 combined mpg |
| 4MATIC Coupe |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
22 city mpg | 30 hwy mpg | 26 combined mpg |
2023 Mercedes-Benz S 450 Gas Mileage (Metric)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| 4MATIC SUV |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
13.0 city L/100 km | 10.0 hwy L/100 km | 11.0 combined L/100 km |
| 4MATIC Coupe |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
11.0 city L/100 km | 8.0 hwy L/100 km | 9.0 combined L/100 km |
2022 Mercedes-Benz S 450 Gas Mileage
Depending on trim level, the 2022 Mercedes-Benz S 450 gas mileage is from 21 to 26 miles per gallon combined.
In the city, the 2022 S 450 gas mileage is from 18 to 22 miles per gallon, depending on the trim.
On the highway, the 2022 S 450 gas mileage is from 24 to 30 miles per gallon, depending on the trim.
2022 Mercedes-Benz S 450 Gas Mileage (Imperial)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| 4MATIC SUV |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
18 city mpg | 24 hwy mpg | 21 combined mpg |
| 4MATIC Coupe |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
22 city mpg | 30 hwy mpg | 26 combined mpg |
2022 Mercedes-Benz S 450 Gas Mileage (Metric)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| 4MATIC SUV |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
13.0 city L/100 km | 10.0 hwy L/100 km | 11.0 combined L/100 km |
| 4MATIC Coupe |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
11.0 city L/100 km | 8.0 hwy L/100 km | 9.0 combined L/100 km |
2021 Mercedes-Benz S 450 Gas Mileage
Depending on trim level, the 2021 Mercedes-Benz S 450 gas mileage is from 22 to 26.5 miles per gallon combined.
In the city, the 2021 S 450 gas mileage is from 20 to 23 miles per gallon, depending on the trim.
On the highway, the 2021 S 450 gas mileage is from 24 to 30 miles per gallon, depending on the trim.
2021 Mercedes-Benz S 450 Gas Mileage (Imperial)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| SUV |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
20 city mpg | 24 hwy mpg | 22 combined mpg |
| Sedan |
3.0L | Intercooled Turbo | Hybrid | I6 | 9 Spd Auto w/OD | RWD |
23 city mpg | 30 hwy mpg | 26.5 combined mpg |
| Sedan |
3.0L | Intercooled Turbo | Hybrid | I6 | 9 Spd Auto w/OD | AWD |
22 city mpg | 29 hwy mpg | 25.5 combined mpg |
2021 Mercedes-Benz S 450 Gas Mileage (Metric)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| SUV |
3.0L | Intercooled Turbo | I6 | 9 Spd Auto w/OD | AWD |
12.0 city L/100 km | 10.0 hwy L/100 km | 11.0 combined L/100 km |
| Sedan |
3.0L | Intercooled Turbo | Hybrid | I6 | 9 Spd Auto w/OD | RWD |
10.0 city L/100 km | 8.0 hwy L/100 km | 9.0 combined L/100 km |
| Sedan |
3.0L | Intercooled Turbo | Hybrid | I6 | 9 Spd Auto w/OD | AWD |
11.0 city L/100 km | 8.0 hwy L/100 km | 9.0 combined L/100 km |
2020 Mercedes-Benz S 450 Gas Mileage
Depending on trim level, the 2020 Mercedes-Benz S 450 gas mileage is from 23 to 23.5 miles per gallon combined.
In the city, the 2020 S 450 gas mileage is from 18 to 19 miles per gallon, depending on the trim.
On the highway, the 2020 S 450 gas mileage is 28 miles per gallon.
2020 Mercedes-Benz S 450 Gas Mileage (Imperial)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
19 city mpg | 28 hwy mpg | 23.5 combined mpg |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
18 city mpg | 28 hwy mpg | 23 combined mpg |
| SClass S 450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
19 city mpg | 28 hwy mpg | 23.5 combined mpg |
| SClass S 450 4MATIC Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
18 city mpg | 28 hwy mpg | 23 combined mpg |
2020 Mercedes-Benz S 450 Gas Mileage (Metric)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
12.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
13.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
| SClass S 450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
12.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
| SClass S 450 4MATIC Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
13.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
2019 Mercedes-Benz S 450 Gas Mileage
Depending on trim level, the 2019 Mercedes-Benz S 450 gas mileage is from 23 to 23.5 miles per gallon combined.
In the city, the 2019 S 450 gas mileage is from 18 to 19 miles per gallon, depending on the trim.
On the highway, the 2019 S 450 gas mileage is 28 miles per gallon.
2019 Mercedes-Benz S 450 Gas Mileage (Imperial)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
19 city mpg | 28 hwy mpg | 23.5 combined mpg |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
18 city mpg | 28 hwy mpg | 23 combined mpg |
| SClass S 450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
19 city mpg | 28 hwy mpg | 23.5 combined mpg |
| SClass S 450 4MATIC Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
18 city mpg | 28 hwy mpg | 23 combined mpg |
2019 Mercedes-Benz S 450 Gas Mileage (Metric)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
12.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
13.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
| SClass S 450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
12.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
| SClass S 450 4MATIC Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
13.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
2018 Mercedes-Benz S 450 Gas Mileage
Depending on trim level, the 2018 Mercedes-Benz S 450 gas mileage is from 23 to 23.5 miles per gallon combined.
In the city, the 2018 S 450 gas mileage is from 18 to 19 miles per gallon, depending on the trim.
On the highway, the 2018 S 450 gas mileage is 28 miles per gallon.
2018 Mercedes-Benz S 450 Gas Mileage (Imperial)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
19 city mpg | 28 hwy mpg | 23.5 combined mpg |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
18 city mpg | 28 hwy mpg | 23 combined mpg |
2018 Mercedes-Benz S 450 Gas Mileage (Metric)
| Trim |
Engine | Transmission | Drivetrain |
City | Highway | Combined Mileage |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | RWD |
12.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
| SClass S450 Sedan |
3.0L | Twin Turbo | V6 | 9 Spd Auto w/OD | AWD |
13.0 city L/100 km | 8.0 hwy L/100 km | 10.0 combined L/100 km |
Mercedes-Benz S 450 Gas Mileage Data Brought To You By AutoPadre
Mercedes-Benz S 450 Gas Mileage Comparisons By Year