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The Mercedes-Benz GLS 580 gas mileage is 16 to 18.5 miles per gallon as specified in our data below, organized by trim, option package, and model year.
For example, the 2027 Mercedes-Benz GLS 580 4MATIC trim model has a combined gas mileage of 16 miles per gallon, while the 2020 Mercedes-Benz GLS 580 GLS 580 4MATIC has a combined gas mileage of 18.5 miles per gallon.
In the city, the GLS 580 gas mileage is 14 to 16 miles per gallon depending on the trim and model year.
On the highway, the GLS 580 gas mileage is 19 to 21 miles per gallon depending on the trim and model year.
Note: The gas mileage shown for hybrid vehicles is the miles per gallon equivalent.
Check out the Gas Mileage specifications for other makes and models.
The 2027 Mercedes-Benz GLS 580 gas mileage is 16 miles per gallon combined.
In the city, the 2027 GLS 580 gas mileage is 14 miles per gallon.
On the highway, the 2027 GLS 580 gas mileage is 20 miles per gallon.
| Trim | Engine | Transmission | Drivetrain | City | Highway | Combined Mileage |
|---|---|---|
| 4MATIC SUV | 4.0L | Turbo | Hybrid | 8 Cyl. | 9 Spd Auto w/OD | AWD | 14 city mpg | 20 hwy mpg | 16 combined mpg |
| Trim | Engine | Transmission | Drivetrain | City | Highway | Combined Mileage |
|---|---|---|
| 4MATIC SUV | 4.0L | Turbo | Hybrid | 8 Cyl. | 9 Spd Auto w/OD | AWD | 16.8 city L/100 km | 11.8 hwy L/100 km | 14.7 combined L/100 km |
The 2026 Mercedes-Benz GLS 580 gas mileage is 16 miles per gallon combined.
In the city, the 2026 GLS 580 gas mileage is 14 miles per gallon.
On the highway, the 2026 GLS 580 gas mileage is 20 miles per gallon.
| Trim | Engine | Transmission | Drivetrain | City | Highway | Combined Mileage |
|---|---|---|
| 4MATIC SUV | 4.0L | Turbo | Hybrid | 8 Cyl. | 9 Spd Auto w/OD | AWD | 14 city mpg | 20 hwy mpg | 16 combined mpg |
| Trim | Engine | Transmission | Drivetrain | City | Highway | Combined Mileage |
|---|---|---|
| 4MATIC SUV | 4.0L | Turbo | Hybrid | 8 Cyl. | 9 Spd Auto w/OD | AWD | 16.8 city L/100 km | 11.8 hwy L/100 km | 14.7 combined L/100 km |
The 2025 Mercedes-Benz GLS 580 gas mileage is 17 miles per gallon combined.
In the city, the 2025 GLS 580 gas mileage is 14 miles per gallon.
On the highway, the 2025 GLS 580 gas mileage is 19 miles per gallon.
| Trim | Engine | Transmission | Drivetrain | City | Highway | Combined Mileage |
|---|---|---|
| 4MATIC Hybrid | 4.0L | Turbo | 8 Cyl. | Hybrid | 9 Spd Auto w/OD | AWD | 14 city mpg | 19 hwy mpg | 17 combined mpg |
| Trim | Engine | Transmission | Drivetrain | City | Highway | Combined Mileage |
|---|---|---|
| 4MATIC Hybrid | 4.0L | Turbo | 8 Cyl. | Hybrid | 9 Spd Auto w/OD | AWD | 16.8 city L/100 km | 12.4 hwy L/100 km | 13.8 combined L/100 km |
The 2020 Mercedes-Benz GLS 580 gas mileage is 18.5 miles per gallon combined.
In the city, the 2020 GLS 580 gas mileage is 16 miles per gallon.
On the highway, the 2020 GLS 580 gas mileage is 21 miles per gallon.
| Trim | Engine | Transmission | Drivetrain | City | Highway | Combined Mileage |
|---|---|---|
| GLS 580 4MATIC SUV | 4.0L | Twin Turbo | V8 | 9 Spd Auto w/OD | AWD | 16 city mpg | 21 hwy mpg | 18.5 combined mpg |
| Trim | Engine | Transmission | Drivetrain | City | Highway | Combined Mileage |
|---|---|---|
| GLS 580 4MATIC SUV | 4.0L | Twin Turbo | V8 | 9 Spd Auto w/OD | AWD | 15.0 city L/100 km | 11.0 hwy L/100 km | 13.0 combined L/100 km |

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