Mercedes-Benz E 350 Gas Mileage (2006-2027)

The Mercedes-Benz E 350 gas mileage is 18.5 to 29 miles per gallon as specified in our data below, organized by trim, option package, and model year.

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For example, the 2009 Mercedes-Benz E 350 Base trim model has a combined gas mileage of 18.5 miles per gallon, while the 2025 Mercedes-Benz E 350 4MATIC has a combined gas mileage of 29 miles per gallon.

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In the city, the E 350 gas mileage is 16 to 98 miles per gallon depending on the trim and model year.

On the highway, the E 350 gas mileage is 21 to 33 miles per gallon depending on the trim and model year.

Note: The gas mileage shown for hybrid vehicles is the miles per gallon equivalent.

Check out the Gas Mileage specifications for other makes and models.

2027 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2027 Mercedes-Benz E 350 gas mileage is from 27 to 28 miles per gallon combined.

In the city, the 2027 E 350 gas mileage is from 24 to 25 miles per gallon, depending on the trim.

On the highway, the 2027 E 350 gas mileage is 33 miles per gallon.

2026 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2026 Mercedes-Benz E 350 gas mileage is from 27 to 28 miles per gallon combined.

In the city, the 2026 E 350 gas mileage is from 24 to 25 miles per gallon, depending on the trim.

On the highway, the 2026 E 350 gas mileage is 33 miles per gallon.

2025 Mercedes-Benz E 350 Gas Mileage

The 2025 Mercedes-Benz E 350 gas mileage is 29 miles per gallon combined.

In the city, the 2025 E 350 gas mileage is from 24 to 25 miles per gallon, depending on the trim.

On the highway, the 2025 E 350 gas mileage is 33 miles per gallon.

2024 Mercedes-Benz E 350 Gas Mileage

The 2024 Mercedes-Benz E 350 gas mileage is 29 miles per gallon combined.

In the city, the 2024 E 350 gas mileage is 24 miles per gallon.

On the highway, the 2024 E 350 gas mileage is 33 miles per gallon.

2023 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2023 Mercedes-Benz E 350 gas mileage is from 22 to 27 miles per gallon combined.

In the city, the 2023 E 350 gas mileage is from 20 to 98 miles per gallon, depending on the trim.

On the highway, the 2023 E 350 gas mileage is from 24 to 31 miles per gallon, depending on the trim.

2022 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2022 Mercedes-Benz E 350 gas mileage is from 22.5 to 27 miles per gallon combined.

In the city, the 2022 E 350 gas mileage is from 19 to 23 miles per gallon, depending on the trim.

On the highway, the 2022 E 350 gas mileage is from 26 to 31 miles per gallon, depending on the trim.

2021 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2021 Mercedes-Benz E 350 gas mileage is from 22.5 to 26.5 miles per gallon combined.

In the city, the 2021 E 350 gas mileage is from 19 to 22 miles per gallon, depending on the trim.

On the highway, the 2021 E 350 gas mileage is from 26 to 31 miles per gallon, depending on the trim.

2020 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2020 Mercedes-Benz E 350 gas mileage is from 22.5 to 27.5 miles per gallon combined.

In the city, the 2020 E 350 gas mileage is from 19 to 23 miles per gallon, depending on the trim.

On the highway, the 2020 E 350 gas mileage is from 26 to 32 miles per gallon, depending on the trim.

2018 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2018 Mercedes-Benz E 350 gas mileage is from 20 to 20.5 miles per gallon combined.

In the city, the 2018 E 350 gas mileage is 18 miles per gallon.

On the highway, the 2018 E 350 gas mileage is from 22 to 23 miles per gallon, depending on the trim.

2017 Mercedes-Benz E 350 Gas Mileage

The 2017 Mercedes-Benz E 350 gas mileage is 20.5 miles per gallon combined.

In the city, the 2017 E 350 gas mileage is 18 miles per gallon.

On the highway, the 2017 E 350 gas mileage is 23 miles per gallon.

2016 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2016 Mercedes-Benz E 350 gas mileage is from 19.5 to 24.5 miles per gallon combined.

In the city, the 2016 E 350 gas mileage is from 17 to 20 miles per gallon, depending on the trim.

On the highway, the 2016 E 350 gas mileage is from 22 to 29 miles per gallon, depending on the trim.

2015 Mercedes-Benz E 350 Gas Mileage

The 2015 Mercedes-Benz E 350 gas mileage is 23.5 miles per gallon combined.

In the city, the 2015 E 350 gas mileage is 20 miles per gallon.

On the highway, the 2015 E 350 gas mileage is 27 miles per gallon.

2014 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2014 Mercedes-Benz E 350 gas mileage is from 22.5 to 25 miles per gallon combined.

In the city, the 2014 E 350 gas mileage is from 19 to 21 miles per gallon, depending on the trim.

On the highway, the 2014 E 350 gas mileage is from 26 to 29 miles per gallon, depending on the trim.

2013 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2013 Mercedes-Benz E 350 gas mileage is from 23 to 27 miles per gallon combined.

In the city, the 2013 E 350 gas mileage is from 19 to 22 miles per gallon, depending on the trim.

On the highway, the 2013 E 350 gas mileage is from 27 to 32 miles per gallon, depending on the trim.

2012 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2012 Mercedes-Benz E 350 gas mileage is from 23 to 26.5 miles per gallon combined.

In the city, the 2012 E 350 gas mileage is from 18 to 21 miles per gallon, depending on the trim.

On the highway, the 2012 E 350 gas mileage is from 27 to 32 miles per gallon, depending on the trim.

2011 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2011 Mercedes-Benz E 350 gas mileage is from 19.5 to 27.5 miles per gallon combined.

In the city, the 2011 E 350 gas mileage is from 16 to 22 miles per gallon, depending on the trim.

On the highway, the 2011 E 350 gas mileage is from 23 to 33 miles per gallon, depending on the trim.

2010 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2010 Mercedes-Benz E 350 gas mileage is from 20 to 22 miles per gallon combined.

In the city, the 2010 E 350 gas mileage is from 16 to 18 miles per gallon, depending on the trim.

On the highway, the 2010 E 350 gas mileage is from 24 to 26 miles per gallon, depending on the trim.

2009 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2009 Mercedes-Benz E 350 gas mileage is from 18.5 to 20.5 miles per gallon combined.

In the city, the 2009 E 350 gas mileage is from 16 to 17 miles per gallon, depending on the trim.

On the highway, the 2009 E 350 gas mileage is from 21 to 24 miles per gallon, depending on the trim.

2008 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2008 Mercedes-Benz E 350 gas mileage is from 18.5 to 20.5 miles per gallon combined.

In the city, the 2008 E 350 gas mileage is from 16 to 17 miles per gallon, depending on the trim.

On the highway, the 2008 E 350 gas mileage is from 21 to 24 miles per gallon, depending on the trim.

2007 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2007 Mercedes-Benz E 350 gas mileage is from 21 to 22.5 miles per gallon combined.

In the city, the 2007 E 350 gas mileage is from 18 to 19 miles per gallon, depending on the trim.

On the highway, the 2007 E 350 gas mileage is from 24 to 26 miles per gallon, depending on the trim.

2006 Mercedes-Benz E 350 Gas Mileage

Depending on trim level, the 2006 Mercedes-Benz E 350 gas mileage is from 21 to 23 miles per gallon combined.

In the city, the 2006 E 350 gas mileage is from 18 to 19 miles per gallon, depending on the trim.

On the highway, the 2006 E 350 gas mileage is from 24 to 27 miles per gallon, depending on the trim.